Billing and Coding: C-Reactive Protein High Sensitivity Testing (hsCRP) (A56643)


Related Local Coverage Determination (LCD)
L34856-C-Reactive Protein High Sensitivity Testing (hsCRP)


Contractor NameContract NumberStates
Novitas Solutions, Inc. 04111 - A and B MAC Colorado
04112 - A and B MAC Colorado
04211 - A and B MAC New Mexico
04212 - A and B MAC New Mexico
04311 - A and B MAC Oklahoma
04312 - A and B MAC Oklahoma
04411 - A and B MAC Texas
04412 - A and B MAC Texas
04911 - A and B MAC Colorado
New Mexico
Oklahoma
Texas
07101 - A and B MAC Arkansas
07102 - A and B MAC Arkansas
07201 - A and B MAC Louisiana
07202 - A and B MAC Louisiana
07301 - A and B MAC Mississippi
07302 - A and B MAC Mississippi
12101 - A and B MAC Delaware
12102 - A and B MAC Delaware
12201 - A and B MAC District of Columbia
12202 - A and B MAC District of Columbia
12301 - A and B MAC Maryland
12302 - A and B MAC Maryland
12401 - A and B MAC New Jersey
12402 - A and B MAC New Jersey
12501 - A and B MAC Pennsylvania
12502 - A and B MAC Pennsylvania
12901 - A and B MAC Delaware
District of Columbia
Maryland
New Jersey
Pennsylvania

Article Information

Article ID Number: A56643 Status: R- Retired

Article Title: Billing and Coding: C-Reactive Protein High Sensitivity Testing (hsCRP)

Original Article Effective Date: 06/27/2019

Revision Effective Date: 11/07/2019

Article Text:

Refer to the Novitas Local Coverage Determination (LCD) L34856, C-Reactive Protein High Sensitivity Testing (hsCRP), for reasonable and necessary requirements and frequency limitations.

The Current Procedural Terminology (CPT)/Healthcare Common Procedure Coding System (HCPCS) code(s) may be subject to National Correct Coding Initiative (NCCI) edits. This information does not take precedence over NCCI edits. Please refer to NCCI for correct coding guidelines and specific applicable code combinations prior to billing Medicare.

Coding Guidance

CPT code 86140 is not to be used in place of CPT code 86141, which represents high sensitivity C-reactive protein (hsCRP) testing.

Frequency Limitations

Consistent with the related LCD, no more than 3 services of CPT code 86141 may be reported per patients lifetime.

Coding Information
Bill Type Codes:

Contractors may specify Bill Types to help providers identify those Bill Types typically used to report this service. Absence of a Bill Type does not guarantee that the policy does not apply to that Bill Type. Complete absence of all Bill Types indicates that coverage is not influenced by Bill Type and the policy should be assumed to apply equally to all claims.

12Hospital Inpatient (Medicare Part B only)
13Hospital Outpatient
14Hospital - Laboratory Services Provided to Non-patients
22Skilled Nursing - Inpatient (Medicare Part B only)
23Skilled Nursing - Outpatient
72Clinic - Hospital Based or Independent Renal Dialysis Center
83Ambulatory Surgery Center
85Critical Access Hospital

Revenue Codes:

Contractors may specify Revenue Codes to help providers identify those Revenue Codes typically used to report this service. In most instances Revenue Codes are purely advisory; unless specified in the policy services reported under other Revenue Codes are equally subject to this coverage determination. Complete absence of all Revenue Codes indicates that coverage is not influenced by Revenue Code and the policy should be assumed to apply equally to all Revenue Codes.

0300 Laboratory - General Classification
0301 Laboratory - Chemistry
0302 Laboratory - Immunology
0303 Laboratory - Renal Patient (Home)
0304 Laboratory - Non-Routine Dialysis
0305 Laboratory - Hematology
0306 Laboratory - Bacteriology & Microbiology
0307 Laboratory - Urology
0309 Laboratory - Other Laboratory

CPT/HCPCS Codes:

Group 1 Paragraph:

Note: Providers are reminded to refer to the long descriptors of the CPT codes in their CPT book.



Group 1 CPT Codes:
86141 C-REACTIVE PROTEIN; HIGH SENSITIVITY (HSCRP)


ICD-10 Codes That Are Covered

It is the provider’s responsibility to select codes carried out to the highest level of specificity and selected from the ICD-10-CM code book appropriate to the year in which the service is rendered for the claim(s) submitted.

Medicare is establishing the following limited coverage for CPT/HCPCS codes: 86141.

Note: Use ICD-10-CM code Z74.09 and Z78.9 for patients at intermediate risk for CAD who do not have elevated lipids (i.e., do not meet criteria to use ICD-10-CM codes E78.00-E78.3 or E78.49).

E78.00 Pure hypercholesterolemia, unspecified
E78.01 Familial hypercholesterolemia
E78.1 Pure hyperglyceridemia
E78.2 Mixed hyperlipidemia
E78.3 Hyperchylomicronemia
E78.49 Other hyperlipidemia
I25.10 Atherosclerotic heart disease of native coronary artery without angina pectoris
Z74.09 Other reduced mobility
Z78.9 Other specified health status
ICD-10 Codes That Are Not Covered

XX000


Revision History Information
Revision History DateRevision History NumberRevision History Explanation
04/10/2025
R2

This article is being retired effective for dates of service on and after 04/10/2025 in response to the LCD being retired.

11/07/2019
R1

Article revised and published on 11/07/2019. Consistent with CMS Change Request 10901, all coding information from the related LCD has been placed into this article. Due to system changes, the order of the Coding Section has been revised and new sections for CPT/HCPCS Modifiers and Other Coding Information have been added.