The information contained in this website has been compiled by CodeMap, L.L.C. to assist Abbott customers. CodeMap, L.L.C. remains solely responsible for its content. The information provided is for general educational purposes only and may not be conclusive or exhaustive. Recent changes in applicable law, regulations and interpretations may not be reflected in the information contained herein.
For technical questions, please contact Dr. Charles Root.
For other questions, please contact the Abbott Reimbursement Helpline at (800) 553-7042, option 6.
Fees reflect revised 2021 Physician Fee Schedule Updated 1/5/2021. Source
The Coronavirus Aid, Relief, and Economic Security (CARES) Act suspended
the payment adjustment percentage of 2% applied to all Medicare Fee-For-Service (FFS) claims from May 1
through December 31. The Consolidated Appropriations Act, 2021, signed into law on December 27, extends
the suspension period to March 31, 2021. An Act to Prevent Across-the-Board Direct Spending Cuts, and for Other Purposes, signed into law on April 14, 2021, extends the suspension period to December 31, 2021.
Click here for more information.
Fees Reflect 2021 CMS Medicare Fee Schedules
Vysis ALK Break Apart FISH Probes Kit
Morphometric analysis, in situ hybridization (quantitative or semi-quantitative), using computer-assisted technology, per specimen; each multiplex probe stain procedure
Procedure Code: 88374 (1) X 1 (2)
|Medicare Reimbursement Amount|
Morphometric analysis, in situ hybridization (quantitative or semi-quantitative), manual, per specimen; each multiplex probe stain procedure
Procedure Code: 88377 (1) X 1 (2)
|Medicare Reimbursement Amount|
When enumeration is performed by a cytotechnologist:
|Procedure Code||Procedure Description||Reimbursement Amount|| Units Billed
|88271||Molecular cytogenetics; DNA probe, each (eg, FISH)|| $ 21.42|
|88275||Molecular cytogenetics; interphase in situ hybridization, analyze 100-300 cells|| $ 51.19|
|88291*||Cytogenetics and molecular cytogenetics, interpretation and report || N/A $ 33.50|
* Code 88291 may be reported if a separate report is provided by a pathologist. The findings must be in writing and signed.
(1) Tests using procedure codes 88374 and 88377 are on the Medicare Part B Physician Fee Schedule and require physician or pathologist review and interpretation. If the test is interpreted by a cytotechnologist, procedure codes 88271 and 88275 are applicable. Procedure code 88291 may be reported if a separate report is provided by a pathologist. The findings must be in writing and signed. The January 2016 National Correct Coding Initiative Manual (Chapter 10, page 15) notes:
"When in situ hybridization is performed on tissue or cellular specimens by a non-physician (provider other than M.D./D.O.), it should be reported using appropriate CPT codes in the range 88271-88275."
"The physician (limited to M.D./D.O.) work component of 88364-88369, 88373, 88374, 88377 requires that a physician (limited to M.D./D.O.) rather than laboratory scientist or technician read, quantitate (88367-88369, 88373, 88374, 88377), and interpret the tissues/cells stained with the probe(s). If this work is performed by a laboratory scientist or technician, CPT codes 88271-88275 should be reported."
(2) Although the code descriptors indicate that the unit of service is for each multiplex probe staining procedure per specimen, the January 2016 edition of the National Correct Coding Initiative Manual (Chapter 10, page 22) indicates the following:
"The unit of service for in situ hybridization reported as CPT codes 88364-88369, 88373, 88374, 88377 is each single or multiplex probe staining procedure per specimen. If a single or multiplex probe staining procedure is performed on multiple blocks from a surgical specimen, multiple slides from a cytologic specimen, or multiple slides from a hematologic specimen, only one unit of service may be reported for each separate specimen. Physicians should not report more than one unit of service for CPT codes 88366, 88374, or 88377 per specimen for each multiplex probe staining procedure even if it contains multiple separately interpretable probes."
PLEASE consult with your payer to confirm the appropriate unit of service to report for this test.
LOINC Codes-Updated 3/29/2018
Under the MolDx program, certain molecular tests require a Z-Code(TM) identifier in addition to the appropriate CPT code. Services within the scope of this program require the Z-Code(TM) to be submitted as additional information at the time of claim submission in order to be fully adjudicated Laboratories performing these molecular tests may be required to register with the MolDx program for each molecular pathology test they furnish. For more information on the MolDx program, registration and covered procedures, please click here: https://www.palmettogba.com/palmetto/MolDX.nsf
The information contained in this website has been compiled by CodeMap, L.L.C. to assist Abbott customers in preparing and submitting claims to Federal health care programs and CodeMap, L.L.C. remains solely responsible for its content. The information provided is for general educational purposes only and may not be conclusive or exhaustive. Recent changes in applicable law, regulations and interpretations may not be reflected in the information contained herein.
Abbott assumes no responsibility for omissions or errors contained in this website. Abbott does not guarantee that the use of any information provided herein will result in coverage or payment by Federal health care programs at any particular level. Many factors affect Federal health care program reimbursement, not all of which may be described in the information provided. Website users are encouraged to seek individual legal and/or coding guidance. IN PROVIDING THIS WEBSITE, ABBOTT MAKES NO WARRANTIES, EXPRESS, IMPLIED OR STATUTORY, INCLUDING, BUT NOT LIMITED TO, WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND/OR NON-INFRINGEMENT.
Abbott is not responsible for any actions taken by website users in billing Medicare or Medicaid for Abbott products, equipment or devices, including but not limited to, any billing and/or coding errors. Website users rely on the information contained in this website at their own risk and should check with the individual Federal health care program contractors to verify coverage, coding and payment.
As a courtesy to its customers, Abbott provides the most accurate and up-to-date information available, but it is subject to change and interpretation. The customer is ultimately responsible for determining the appropriate codes, coverage, and payment policies for individual patients. Abbott does not guarantee third party coverage or payment for our products or reimburse customers for claims that are denied by third party payors.
This website is a private website and is not associated, endorsed or authorized by the Department of Health and Human Services, the Center for Medicare and Medicaid Services or any other public or government organization or agency.
© 2019 Abbott. All rights reserved. All trademarks referenced are trademarks of either the Abbott group of companies or their respective owners.
CPT copyright 2020 American Medical Association. All rights reserved.