National Coverage Determination
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CMS Policy Number: 190.25
Description: Alpha-fetoprotein (AFP) is a polysaccharide found in some carcinomas. It is effective as a biochemical marker for monitoring the response of certain malignancies to therapy.
AFP is useful for the diagnosis of hepatocellular carcinoma in high-risk patients (such as alcoholic cirrhosis, cirrhosis of viral etiology, hemochromatosis, and alpha 1-antitrypsin deficiency) and in separating patients with benign hepatocellular neoplasms or metastases from those with hepatocellular carcinoma and, as a non-specific tumor associated antigen, serves in marking germ cell neoplasms of the testis, ovary, retro peritoneum, and mediastinum.
To review all requirements of this policy, please see:
CMS NCD listing by Chapter
Covered ICD-10 Codes.
.... and many more.
|Syphilis of liver and other viscera
|Chronic viral hepatitis B with delta-agent
|Chronic viral hepatitis B without delta-agent
|Chronic viral hepatitis C
|Liver cell carcinoma
|Intrahepatic bile duct carcinoma
|Angiosarcoma of liver
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