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January 2024
October 2023

CMS Transmittals

National Coverage Determination
Procedure Code: 8XXXX
Blood Counts
CMS Policy Number: 190.15
Back to NCD List

Description: Blood counts are used to evaluate and diagnose diseases relating to abnormalities of the blood or bone marrow. These include primary disorders such as anemia, leukemia, polycythemia, thrombocytosis and thrombocytopenia. Many other conditions secondarily affect the blood or bone marrow, including reaction to inflammation and infections, coagulopathies, neoplasms and exposure to toxic substances. Many treatments and therapies affect the blood or bone marrow, and blood counts may be used to monitor treatment effects.

The complete blood count (CBC) includes a hemogram and differential white blood count (WBC). The hemogram includes enumeration of red blood cells, white blood cells, and platelets, as well as the determination of hemoglobin, hematocrit, and indices.

The symptoms of hematological disorders are often nonspecific, and are commonly encountered in patients who may or may not prove to have a disorder of the blood or bone marrow. Furthermore, many medical conditions that are not primarily due to abnormalities of blood or bone marrow may have hematological manifestations that result from the disease or its treatment. As a result, the CBC is one of the most commonly indicated laboratory tests.

In patients with possible hematological abnormalities, it may be necessary to determine the hemoglobin and hematocrit, to calculate the red cell indices, and to measure the concentration of white blood cells and platelets. These measurements are usually performed on a multichannel analyzer that measures all of the parameters on every sample. Therefore, laboratory assessments routinely include these measurements.

To review all requirements of this policy, please see: CMS NCD listing by Chapter

Covered ICD-10 Codes.

A00.0Cholera due to Vibrio cholerae 01, biovar cholerae
A00.1Cholera due to Vibrio cholerae 01, biovar eltor
A00.9Cholera, unspecified
A01.00Typhoid fever, unspecified
A01.01Typhoid meningitis
A01.02Typhoid fever with heart involvement
A01.03Typhoid pneumonia
A01.04Typhoid arthritis
A01.05Typhoid osteomyelitis
A01.09Typhoid fever with other complications
.... and many more.

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